VARIABLE HDL > 40 mg/dL TG < 150 mg/dL (n=55) HDL > 40 mg/dL TG > 150 mg/dL (n=21) HDL < 40 mg/dL TG < 150 mg/dL (n=42) HDL < 40 mg/dL TG > 150 mg/dL (n=57) P
LDL-C 117 (84, 143) 120 (106, 152) 103 (78, 127) 94 (67, 119) < 0.001
Triglycerides 83 (52, 111) 188 (179, 226) 92 (70, 111) 254 (186, 371) < 0.001
RLP-C 7 (6, 8) 12 (9, 18) 6 (5, 8) 18 (12, 26) < 0.001
NEFA (mEq/L) 0.4 (0.2, 0.5) 0.3 (0.2, 0.4) 0.3 (0.2, 0.4) 0.3 (0.2, 0.4) 0.66
Apo-B 78 ± 18 99 ± 16 75 ± 17 93 ± 20 < 0.001
Lp(a) 23 (14, 48) 15 (7, 53) 17 (4, 41) 14 (7, 34) 0.11
HDL-C 51 (46, 62) 44 (42, 50) 32 (27, 35) 29 (25, 34) < 0.001
HDL-TG 14 (11, 19) 26 (16, 30) 13 (9, 17) 20 (17, 29) < 0.001
ApoA-I 145 ± 24 148 ± 24 106 ± 16 111 ± 18 < 0.001
ApoA-II 37 ± 9 45 ± 9 30 ± 9 33 ± 8 < 0.001
ApoE 3.8 (3.5, 4.6) 4.5 (4.0, 5.8) 3.5 (2.9, 3.9) 5.4 (4.3, 7.2) < 0.001
Preβ-1 37 (29, 47) 43 (33, 47) 30 (22, 36) 39 (31, 46) 0.001
Preβ-2 2.6 (1.3, 3.7) 1.7 (1.2, 2.2) 1.3 (0.9, 2.1) 1.2 (0.9, 2.3) < 0.001
α-1 18.9 (14.9, 29.3) 10.9 (8.1, 12.1) 8.8 (6.7, 11.8) 5.8 (3.5, 8.9) < 0.001
α-2 35 (28, 41) 36 (33, 38) 26 (21, 30) 24 (19, 27) < 0.001
α-3 22 (17, 29) 30 (24, 33) 23 (16, 26) 20 (17, 26) 0.006
α-4 6.9 (5.9, 10.5) 9.5 (7.7, 11.4) 7.3 (6.1, 9.3) 6.2 (4.7, 8.1) 0.013
Preα-1 5.0 (2.5, 9.9) 2.6 (0.6, 3.9) 1.9 (0.6, 3.6) 1.3 (0.3, 2.5) < 0.001
Preα-2 5.0 (2.9, 8.2) 3.4 (2.5, 6.5) 3.5 (2.1, 4.6) 3.2 (2.0, 4.3) 0.002
Preα-3 2.8 (1.9, 4.3) 3.5 (2.1, 5.4) 2.4 (1.8, 3.5) 2.7 (1.9, 3.4) 0.28
Preα-4 1.2 (0.5, 1.9) 1.5 (0.7, 2.1) 0.9 (0.6, 1.4) 1.2 (0.7, 1.5) 0.17
CETP (μg/mL) 2.2 (1.8, 2.5) 2.2 (1.6, 2.4) 2.2 (1.8, 2.7) 2.1 (1.7, 2.6) 0.80
LCAT (μg/mL) 6.9 (5.7, 7.7) 8.2 (7.4, 10.1) 5.9 (5.3, 6.9) 7.7 (6.8, 8.7) < 0.001
CETP Activity (μg/mL/hour) -0.41 (-1.54, 1.01) 0.33 (-0.85, 2.44) 0.02 (-1.21, 0.87) 1.81 (0.35, 2.98) 0.001
LCAT Activity (μg/mL/hour) 13 (7, 26) 16 (12, 24) 12 (7, 23) 20 (13, 28) 0.014
Values are mg/dL or as indicated.
Normally distributed parameters are expressed as average ± SD.
Not normally distributed parameters are expressed as median (min, max).
Table 4b: Lipoprotein-associated parameters in patients, quartiled by HDL-C and TG levels.