Covariates |
No at risk |
No of OIs cases |
Crude Hazard Ratio (95% CI) |
Adjusted Hazard Ratio ( 95% CI) |
P value |
HAART Status
HAART
Pre-ART |
232
232 |
21
156 |
0.06 (0.03, 0.09)
1 |
0.07 (0.03, 0.16)
1 |
<0.001* |
Sex
Male
Female |
167
297 |
91
86 |
1.89 (1.41, 2.54)
1 |
2.19 (1.55, 3.11)
1 |
<0.001* |
Marital status
Married
Single
Divorced
Widowed |
245
58
81
80 |
90
13
43
31 |
1
2.42 (1.67, 3.51)
0.66 (0.37, 1.18)
1.18 (0.78, 1.78) |
1
1.45 (0.95, 2.22)
0.86 (0.47, 1.56)
1.68 (1.08, 2.60) |
0.083
0.618
0.022* |
Age category
15-24
25-34
35-44
>=45 |
121
177
121
45 |
60
66
43
8 |
1
0.38 (0.27, 0.55 )
0.30 (0.20, 0.46)
0.15 (0.07, 0.31) |
1
0.44 (0.29, 0.65)
0.27 (0.17, 0.43)
0.18 (0.08, 0.39) |
<0.001*
<0.001*
<0.001* |
Supportive care
Present
Absent |
166
298 |
51
126 |
1
1.40 (1.01, 1.93) |
1
1.36 (0.98,1.89) |
0.069 |
Prophylaxis B
Yes
No |
279
185 |
72
105 |
0.19 (0.13, 0.26)
1 |
|
|
Prophylaxis F
Yes
No |
193
271 |
86
91 |
1.33 (.99, 1.79)
1 |
|
|
WHO Stage B
Stage I or II
Stage III or IV |
389
75 |
164
13 |
1
0.29 (0.16, 0.50) |
|
|
Functional Status F
Working
Ambulatory and Bedridden |
436
28 |
165
12 |
1
3.33 (2.38, 4.66) |
|
|
Address
Urban
Rural |
365
99 |
121
56 |
1
1.79 (1.30, 2.47) |
1
1.62 (1.15, 2.27) |
0.005* |
Substance use B
Yes
No |
82
382 |
45
132 |
2.50 (1.78, 3.52)
1 |
2.11 (1.46, 3.06)
1 |
<0.001* |
Substance use F
Yes
No |
80
384 |
43
134 |
2.21 (1.56, 3.12)
1 |
2.15 (1.47, 3.13)
1 |
<0.001* |
CD4 count B
<200cells/µl
200-349cells/µl
350-499cells/µl
>=500cells/µl |
33
133
144
154 |
16
64
56
41 |
0.07 (.04, 0.14)
0.09 (0.05, 0.15)
1.04 (0.75, 1.45)
1 |
1.16 (0.39, 3.58)
0.86 (0.40, 1.84)
1.71 (1.19, 2.46)
1 |
0.792
0.694
0.004* |
CD4 count F
<200cells/µl
200-349cells/µl
350-499cells/µl
>=500cells/µl |
33
133
144
154 |
16
64
56
41 |
3.15 (1.75, 5.68)
2.09 (1.40, 3.11)
1.69 (1.12, 2.53)
1 |
3.36 (1.86, 6.08)
1.71 (1.13, 2.59)
1.72 (1.14, 2.58)
1 |
<0.001*
0.011*
0.010* |
F =follow up, B= baseline, *= P-value <0.05 is considered as statistically significant |