Treated (n=46) Untreated (n=22) p value
Demographic data      
Age (years) 11.4(2.9) 10.7(2.9) 0.3
Male %(N)†† 52 (24) 59 (13) 0.1
Clinical parameters  
Weight 36.2(11.9) 37.9(14.6) 0.6
BMI 17.8(2.7) 18.8(3.1) 0.2
Systolic blood pressure (mmHg) 102.4(9.2) 107.0(10.3) 0.08
Diastolic blood pressure (mmHg) 60.5(10.2) 62.5(5.9) 0.3
Heart rate (bpm) 80(11) 84(16) 0.2
Glucose (mmol/L) 4.4(0.7) 4.5((0.8) 0.7
High sensitivity CRP (mg/L); median [IQR] 1.1[0.2,2.4] 0.4[1.4,2.4] 0.3
CDC stage (A/C) †† 14/17 13/0 0.001
Viral load median[IQR] 50[50,2175] 17400[11050, 36600] 0.0001
Lipid/ Blood results  
Total cholesterol (mmol/L) 4.3(0.9) 3.5(0.8) 0.002
HDL cholesterol (mmol/L) 1.4(0.5) 0.9(0.3) 0.0001
Lp(α) (mg/L); median [IQR] 46.1[30.6,77.7] 34.7[22.6,67.3] 0.5
Triglycerides (mmol/L); median [IQR] 1.0[0.8,1.3] 0.9[0.6,1.4] 0.7
Anthropometric measurements z-scores (median [IQR]
Waist circumference 0.2[-0.3,0.6] 0.6[0.3,0.8] 0.2
Arm circumference -0.7[-1.3,0.3] -0.2[-1.1, 0.6] 0.3
Thigh circumference -1.1[-2.0,0.1] -0.6[-1.2,-0.1] 0.1
Calf circumference -0.8[-2.2,0.1] -0.9[-1.8,0.2] 0.4
Biceps skin-fold 1.1[0.2,1.9] 1.9[0.8,3.8] 0.05
Triceps skin-fold 0.1[-0.5,1.1] 0.8[-0.1,1.8] 0.2
Subscapular skin-fold 1.8 [0.2,2.9] 1.7[0.3,4.1] 0.9
Suprailiac skin-fold -0.5[-1.1,-0.1] -0.6[-.9,0.4] 0.3
Vascular measurements      
Flow mediated dilation (%) 7.3(3.9) 10.1(4.2) 0.01
Baseline diameter (mm) 2.7(0.5) 2.8((0.5) 0.7
Glyceryltrinitrate mediated dilation (%) 13.8(5.6) 15.8(6.3) 0.2
Values expressed in mean (SD) unless otherwise stated. Comparisons between groups were made using independent t-test. Non-parametric variables were expressed as median [IQR] and comparisons were made between the groups using Mann Whitney analysis. ††: Analysis was performed using the chi-square test.
Table 1: Descriptive characteristics in HIV-infected treated and untreated children.