Variable |
Group A |
Group B |
Group C |
P-value |
N=35 |
N=35 |
N=34 |
A=B |
A=C |
B=C |
AGE |
57 (45 -70) |
40 (24-48) |
52 (25-72) |
0.0001* |
0.1429 |
0.0001* |
HIV PCR /mL |
40(40-48000) |
42700( 40-1850000) |
N/A |
<0.001* |
N/A |
N/A |
AST or SGOT (U/L) |
35.0 (19-86) |
27.0 (13-87) |
23.0 (13-135) |
0.0200* |
0.0064* |
0.6184 |
ALT or SGPT (U/L) |
33.0 (9-122) |
24.0 ( 5-69) |
23 (13-145) |
0.0104* |
0.0310* |
0.7368 |
BUN (mg/dL) |
16 (9-33) |
14 (9-38) |
15 (7-29) |
0.0325* |
0.1149 |
0.6155 |
Creatinine (mg/dL) |
1.0 (0.7-1.7) |
1.0 (0.6-2.1) |
1.0 (0.7-1.3) |
0.4186 |
0.9932 |
0.4324 |
CD4 (cell/mL) |
533 (73-1302) |
342 (77-896) |
843 (435-1319) |
0.0007* |
0.0001* |
0.0001* |
CD38 (mol on CD8) |
1038 (101-2191) |
734 (321-2150) |
484 (192-1019) |
0.0001* |
0.0001* |
0.0061* |
ALP (U/L) |
73(25-130) |
65 (50-145) |
64 (33-108) |
0.2910 |
0.1060 |
0.2950 |
Ostase BAP (mg/L) |
20.9 (9.1-34.2) |
16.4 (10.3-27.6) |
15.8 (7.7-27.3) |
0.0678 |
0.0434* |
0.8319 |
Osteocalin (ng/mL) |
5.2 (1.0-42.5) |
6.9 (3.8-54.3) |
5.3(3.1-9.4) |
0.7260 |
0.2070 |
0.1110 |
TRAP (U/L) |
3.9 (2.5-6.7) |
2.9 (1.2-4.7) |
2.5 (1.6-4.7) |
0.0002* |
0.0001* |
0.0167* |
PTH (pg/mL) |
24.7 (8.3-47.7) |
23.0 ( 12.5-145.2) |
31.6 (16.4-65.9) |
0.1571 |
0.0313* |
0.4245 |
Calcium (mg/dL) |
9.3 (7.9-10.1) |
8.9 (8.1-9.9) |
9.3 ( 8.4-10.8) |
0.1136 |
0.6228 |
0.4090 |
Inorg, Phosphorus (mg/dL) |
3.0 (1.7-3.8) |
3.3 (2.5-6.0) |
3.0 (2.1-4.2) |
0.0016* |
0.1179 |
0.0978 |
|
A=HIV-1 infected men on ART, B=HIV-1 infected men not ART, C=HIV-1uninfected men; N=number of men; mol=molecule; *=significant differences; and N/A=not applicable; |
Table 1: The median, minimum, maximum of blood markers under investigation for each group. |