Variable Group A Group B Group C P-value
N=35 N=35 N=34 A=B      A=C B=C
AGE 57 (45 -70) 40 (24-48) 52 (25-72) 0.0001* 0.1429 0.0001*
HIV PCR /mL 40(40-48000) 42700( 40-1850000) N/A <0.001* N/A N/A
AST or SGOT (U/L) 35.0 (19-86) 27.0 (13-87) 23.0 (13-135) 0.0200* 0.0064* 0.6184
ALT or SGPT (U/L) 33.0 (9-122) 24.0 ( 5-69) 23 (13-145) 0.0104* 0.0310* 0.7368
BUN (mg/dL) 16 (9-33) 14 (9-38) 15 (7-29) 0.0325* 0.1149 0.6155
Creatinine (mg/dL) 1.0 (0.7-1.7) 1.0 (0.6-2.1) 1.0 (0.7-1.3) 0.4186 0.9932 0.4324
CD4  (cell/mL) 533 (73-1302) 342 (77-896) 843 (435-1319) 0.0007* 0.0001* 0.0001*
CD38 (mol on CD8) 1038 (101-2191) 734 (321-2150) 484 (192-1019) 0.0001* 0.0001* 0.0061*
ALP (U/L) 73(25-130) 65 (50-145) 64 (33-108) 0.2910 0.1060 0.2950
Ostase BAP (mg/L) 20.9 (9.1-34.2) 16.4 (10.3-27.6) 15.8 (7.7-27.3) 0.0678 0.0434* 0.8319
Osteocalin (ng/mL) 5.2 (1.0-42.5) 6.9 (3.8-54.3) 5.3(3.1-9.4) 0.7260 0.2070 0.1110
TRAP  (U/L) 3.9 (2.5-6.7) 2.9 (1.2-4.7) 2.5 (1.6-4.7) 0.0002* 0.0001* 0.0167*
PTH  (pg/mL) 24.7 (8.3-47.7) 23.0 ( 12.5-145.2) 31.6 (16.4-65.9) 0.1571 0.0313* 0.4245
Calcium (mg/dL) 9.3 (7.9-10.1) 8.9  (8.1-9.9) 9.3 ( 8.4-10.8) 0.1136 0.6228 0.4090
Inorg, Phosphorus (mg/dL) 3.0 (1.7-3.8) 3.3 (2.5-6.0) 3.0 (2.1-4.2) 0.0016* 0.1179 0.0978
A=HIV-1 infected men on ART, B=HIV-1 infected men not ART, C=HIV-1uninfected men; N=number of men; mol=molecule; *=significant differences; and N/A=not applicable;
Table 1: The median, minimum, maximum of blood markers under investigation for each group.
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