| Characteristic |
(Men’s) Multicenter AIDS Cohort Study |
Women’s Interagency HIV Study |
| |
n=121 |
n=63 |
| Age, mean (SD) |
53.1 (7.5) |
49.1 (8.9) |
| Female, n (%) |
0 (0) |
63 (100) |
| Race, n (%) |
|
|
| White |
100 (82.6) |
23 (36.5) |
| Black |
21 (17.4) |
40 (63.5) |
| Hispanic, n (%) |
3 (2.5) |
5 (7.9) |
| Completed high school, n (%) |
114 (94.2) |
47 (74.6) |
| Marital status, n (%) |
|
|
| Never married |
-- |
21 (33.3) |
| Married |
-- |
22 (34.9) |
| Divorced or widowed |
-- |
20 (31.8) |
| Alcohol consumption, n (%) |
|
|
| None |
69 (57.0) |
38 (60.3) |
| 1-2 drinks per week |
22 (18.2) |
16 (25.4) |
| >2 drinks per week |
30 (24.8) |
9 (14.3) |
| Clinical History |
|
|
| Number of study visits attended, mean (SD) |
35 (16.0) |
26 (6.3) |
| Tobacco use, n (%) |
|
|
| Never |
26 (21.5) |
12 (19.1) |
| Former |
58 (47.9) |
23 (36.5) |
| Current |
37 (30.6) |
28 (44.4) |
| Cumulative pack-years tobacco use, median (IQR) |
8.2 (0-33.2) |
3.0 (0.04-12.4) |
| Asthma diagnosis, n (%) |
15 (12.4) |
22 (34.9) |
| Bronchodilator use in previous 3 months, n (%) |
12 (9.9) |
11 (17.5) |
| Hepatitis C infection, n (%) |
13 (10.7) |
30 (47.6) |
| History of bacterial or Pneumocystis jirovecii pneumonia, n (%) |
40 (33.1) |
14 (22.2) |
| ART use since last visit, n (%) |
104 (86.0) |
51 (81.0) |
| Current CD4 (cells/µL), median (IQR) |
575 (440-794) |
426 (264-677) |
| Nadir CD4 (cells/µL), median (IQR) |
269 (155-358) |
159 (65-286) |
| Current HIV RNA level (copies/mL), median (IQR) |
<40 (40-40) |
102 (48-727) |
| Recreational Drug Use |
|
|
| Percentage of total visits reporting recent drug use, median % (IQR) |
56 (18-87) |
31 (3-75) |
| Any drug use since last visit, n (%) |
59 (48.8) |
25 (39.7) |
| Pulmonary Function |
|
|
| Airflow obstruction |
|
|
| Post-BD FEV1/FVC ratio <0.70, n (%) |
16 (13.2) |
7 (11.1) |
| Post-BD FEV1/FVC ratio, mean (SD) |
0.78 (0.08) |
0.78 (0.07) |
| Diffusion impairment |
|
|
| DLCO % predicted <80%, n (%) |
65 (53.7) |
53 (84.1) |
| DLCO % predicted <60%, n (%) |
16 (13.2) |
23 (36.5) |
| DLCO % predicted, mean (SD) |
79 (19.0) |
65 (14.0) |
| Radiographic emphysema,b n (%) |
64 (65.3) |
9 (15.3) |
