Characteristics Naive* patients Experienced patients
  Without co-infection (N=195) With co-infection (N=61) P** Without co-infection (N=624) With co-infection (N=399) P**
Sex
Male 138 (70.8%) 42 (68.9%) 0,77 427 (68.4%) 293 (73.4%) 0,09
Age in years
Median (range) 39 (18-82) 41 (21-66)   42 (18-79) 43 (22-79)  
Time from HIV-positive in years
Median (range) 1 (0-20) 7.2 (0-24.3) <0,0001 11(0-23.3) 15.2 (0.1-25.3) <0,0001
CDC classification C            
Yes 39(20%) 12 (19.7%) 0,96 204 (32.7%) 123 (30.8%) 0,53
HIV-1 RNA log10 copies per mL
Mean (±SD) 5.2 (± 0.8) 4.8 (± 0.9) <0.01 3.3 (± 1.5) 3.3 (± 1.5) 0.65
>5 log10 copies per mL 109 (65.3%) 23(50%) 0.06 99 (15.9%) 62 (15.5%) 0.89
Missing value 28 15   0 0  
CD4+ cell count in cells per mL
Mean (±SD) 210(±140) 197.7 (±164.5) 0.61 394.3 (±251.7) 341(±244.7) <0.0001
Missing value 26 16   5 5  
ALT Grade          
Normal 102 (81%) 32 (80%) 0,91** 414 (83.5%) 188 (58%)  <0,001
Grade 1/2 22 (17.5%) 7 (17.5%)   77(15.5%) 127(39.2%)  
Grade 3/4 2(1.6%) 1 (2.5%)   5(1%) 9(2.8%)  
Missing 69 21   128 75  
AST Grade
Normal 107 (84.9%) 27 (67.5%) 0.02** 433 (87.2%) 167 (51.3%) <0.001
Grade 1/2 18(13.3%) 11 (28%)   57(11.5%) 149 (45.8%)  
Grade 3/4 1 (0.8%) 2 (5%)   6(1.2%) 9(2.8%)  
Missing 69 21   128 74  
Table 1: Description of baseline characteristics. *”naive patients”: FPV/r used as a part as the first regimen. ** exact fisher test