Crude and Adjusted Analysis: Factors Associated.

Variable	Crude Analysis		Adjusted Analysis*
Variable	Odds Ratio (95% CI)	P value	Odds Ratio (95% CI)	P value
Age in years	1.0 (0.95-1.04)	0.8	-	-
Race/Ethnicity
Non-hispanic white	Reference	-	-	-
Non-hispanic black	1.52 (0.47-4.9)	-	-	-
Other	1.33 (0.18-9.73)	0.78	-	-
Weight in Kg	0.99 (0.97-1.01)	0.33	0.99 (0.96-1.01)	0.24
Gender
Male	Reference	-	-	-
Female	0.5 (0.15-1.66)	0.26	-	-
TDF stopped
No	Reference	-	-	-
Yes	2.54 (0.97-6.64)	0.06	3.76 (1.26-11.27)	0.02
Increase in sCr ≥0.3 mg/dl	1.00 (0.87-1.15)	0.97	0.75 (0.45-1.23)	0.25
Baseline CKD1
No	Reference	-	-	-
Yes	0.16 (0.04-0.68)	0.01	-
HCV Antibody
Negative	Reference	-	-	-
Positive	2.32 (0.69-7.81)	0.18	-	-
Diabetes Mellitus
No	Reference		Reference
Yes	0.63 (0.18-2.2)	0.46	0.29 (0.06-1.48)	0.14
Hypertension
No	Reference		Reference
Yes	1.09 (0.42-2.81)	0.86	1.59 (0.45-5.66)	0.47
Nephrotoxic drugs
No	Reference		Reference
Yes	1.16 (0.46–2.96)	0.76	1.34 (0.43-4.21)	0.61
HIV-1 PVL²
≤75 log10 copies/ml	Reference
>75 log10 copies/ml	0.52 (0.18-1.54)	0.24
CD4 cell count²
≤200 cells/µL	Reference
>200 cells/µL	0.86 (0.33-2.21)	0.75

Table 2: Crude and Adjusted Analysis: Factors Associated with Renal Function Recovery. ¹Adjusted not performed given small number of cases (n = 10); ²At time of HLA test; *Observations with missing data were excluded from analysis. TDF: Tenofovir; sCr: Serum Creatinine; HCV: Hepatitis C Virus; PVL: Plasma Viral Load.

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