Figure 5: Vaccine-induced HIV-specific CD4+ and CD8+ T cells expressing multiple functional markers: The proportion of HIV-specific CD4+ (left) or CD8+ (right) T cells with one, two, three or four functions measured by expression of Granzyme B, IFN-g, IL-2, or TNFα is shown for positive responders from Figure 4. Boxplots show the distribution of responses; the box indicates the median and IQR, whiskers extend to the furthest point within 1.5 times the IQR from the upper or lower quartile.