Gold Standard
    GS+ GS-
Test T+ TP FP
T- FN TN
T+ = Test positive
T- = Test negative
T = True
F = False
P = Positive
N = Negative
GS+ = Gold standard positive
GS- = Gold standard negative
Sensitivity = TP/TP+FN
Specificity = TN/FP+TN
Positive Predictive Value = TP/TP+FP
Negative Predictive Value = TN/FN+TN
Table 2: Binomial classification method for comparing a modality, practice, or test with a gold standard and for calculating sensitivity, specificity, positive predictive value, and negative predictive value.
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