Figure 6: Hepatic cytochrome P-450 (CYP2E1) expression in negative control subcutaneous (s.c) and intramuscular (i.m), positive control of Acetaminophen (APAP) hepatotoxicity, Freund´s adjuvants (FA) administrated s.c or i.m and combination of APAP/FA s.c or APAP/FA i.m mice groups, quantitated by immuno-blotting and densitometry. The averages of the values derived from the control mice were expressed as 100%. The data are presented as the means ± S.D. and were obtained from five mice per group.
(a) represents significative difference when compared with their correspondent control group and APAP treated group, (p< 0.05) (ANOVA followed by Turkey’s post hoc test).