Figure 3: Percentages of CD63 positive activated peripheral blood basophils (Panel A) and median fluorescence intensity of CD193 (CCR3) expression (Panel B) on activated peripheral blood basophils, in patients with mastocytosis (n=19, dark grey boxes) and in healthy individuals (blood donors) (n=19, light grey boxes), at the baseline (unstimulated) and after stimulation with fMLP or with anti-FcεRI.
Boxes extend from the 25th to the 75th percentiles; the line in the middle and the vertical lines represent median values and 95% confidence intervals, respectively. No significant differences (P>0.05) were observed between the % of CD63+ basophils and the MFI of CD193 (CCR3) expression on basophils in patients and in controls using the Mann-Whitney U-test.