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Figure 4: Percentage of HLA-DR+ and CD294 (CRTH2)+ peripheral blood
T cells, in patients with mastocytosis (n=19, dark grey boxes) and healthy
individuals (blood donors) (n=18, light grey boxes). Allophycocyanin conjugated anti-CD3, pacific blue conjugated anti-HLA-DR, and phycoerythrin conjugated anti-CD294 were used in combination with other monoclonal antibodies. Boxes extend from the 25th to the 75th percentiles; the line in the middle and the vertical lines represent median values and 95% confidence intervals, respectively. No significant differences (P> 0.05) were observed between the % of HLA-DR+ and CD294 (CRTH2)+peripheral blood T cells in patients and controls using the Mann-Whitney U-test. |