Figure 3: BAL cytokine analysis in C57BL/6 and Mindin -/- mice Using the cell-free supernatants from the BAL in the C57BL/6 saline (shaded box), Mindin-/- saline (checkered box), C57BL/6 FAP (closed box) and Mindin-/- FAP (open box) a multiplex was performed to assess protein levels reflecting activation of either innate or adaptive immunity including: (A) IL-1β and TNF-α; (B) Th1 cytokines IL-12p70 and IFN-γ; (C) Th2 cytokines IL-13 and IL-4; (D) Th17 cytokine IL-17; (E) chemokines CCL2, CCL4, CXCL1 and CXCL10; and (F) eotaxin. (*P<0.05 between C57BL/6 saline and FAP exposure and C57BL/6 and Mindin-/- FAP exposure, N=6).
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