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| Figure 5: The route of antigen sensitization results in differential inflammatory and AHR responses. WT mice we sensitized to Asp by IT (IT Asp) or IP (IP Asp) administration followed by Asp challenge (n = 6, 8 respectively). Top panels, AHR measured by FlexiVent, Rn - airway resistance, H - tissue elastance. Lower panels, inflammatory cells in BAL fluid and Asp specific immunoglobulin in lung homogenate. * p < 0.05 versus IP Asp. |
