Sheath/core
polymers
Solvents Fiber dia (nm)
Total (core)
Objective of
the study
Reference
Sheath Core
PEO/PEO
PEO/PSU
Water + ethanol
Water + ethanol
Water + ethanol
Chloroform
3000 (2000)
60 (40)
To demonstrate the
feasibility of the co-axial
electrospinning process
Sun et al.
2003 [21]
PCL/Gelatin TFE TFE 100 to 300
(<100)
To demonstrate core-sheath
fiber formation using
bio-degradable materials
Zhang et al.
2004 [8]
PCL/Gelatin TFE TFE 200 to 500
(61 to 180)
To improve mechanical
performance of the nano fiber mat
Huang et al.
2005 [22]
Collagen/PCL HFIP TFE 385 (321) To improve surface bio-compatibility of the nano
fibers for tissue engineering application
Zhang et al.
2005 [10]
PVP/PLA DMF + ethanol DMF + acetone 400 to 500
(200 to 300)
To prepare biodegradable composite nanofiber
structure for possible controlled particle release
application (e.g. drug delivery)
Sun et al.
2006 [39]
Table 2: List of studies using co-axial electrospinning to prepare core-shell nanofibers.
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