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| Figure 6: An example showing the results obtained in a pathway when processed or not by Gene2Path: Illustration of the “Intestinal immune network for IgA Production” using the data from a rainbow trout microarray. (A) Genes (red boxes) found in the Danio rerio pathway (KEGG alias: dre04672) obtained manually from the databases (n=2/55 genes), without the orthology step. (B) Genes found (red boxes) in the same pathway after running the orthology step of the program (n=20/55 genes). IgA have not been identified in fish, but functional similarities with the IgT genes implicated in the Danio rerio orthologous could exist and pathways showed similar trends than most of those pathways described. |
