Time (hr) Concentration (μg/mL) %CV
Rat-1 Rat-2 Rat-3 Mean STDEV
0.25 13.36 17.02 17.75 16.04 2.35 15
0.50 18.42 30.50 24.45 24.45 6.04 25
1.00 16.55 24.37 17.44 19.46 4.28 22
2.00 15.06 9.45 8.75 11.09 3.46 31
4.00 2.94 1.88 1.90 2.24 0.61 27
8.00 BLQ BLQ BLQ NC NC NC
24.00 BLQ BLQ BLQ NC NC NC
NC-Not Calculated
BLQ-Below Limit of Quantitation
Table 3: Plasma concentration levels of CrEL-PEG after oral administration of CrEL at 0.26 g/kg dose.