Figure 5: Defect rate analysis of the factors, X_{1} flow rate: mL/min, X_{2} injection volume: µL, X_{3} initial gradient acetonitrile ratio: % v/v, for the responses, Y_{1} peak area of
STP: mAU.s, Y_{2} peak area of HI443: mAU.s, Y_{3}USP Tailing of STP, and Y_{4} USP Tailing of HI443, shown by: (A) Defect rate profiler. (B) Defect parametric profiler. (C) Gaussian process plot. (D) Marginal model plots, (E) Prediction profiler plot for Log10 defect rate and desirability plot. |