Table 3 | Kinetics of in-vitro release profile..

Drug	Zero order release model		First order release model		Higuchi release model		Korsmeyer-Peppas model
	*K₀^a*	*r₂^b*	*K¹^a*	*r₂^b*	*KH^a*	*r₂^b*	*k^a*	nc	*r₂^b*
STP	0.21	0.52	0.027	0.83	6.63	0.46	0.21	0.11	0.65
HI443	0.28	0.75	0.030	0.94	6.68	0.90	0.07	0.26	0.97

^a Rate constant: K₀ inμg/min; K₁ inmin^-1, K_H inμg/min1/2, k in min^-1
^b Square of correlation coefficient
^c Exponent explaining the drug release mechanisms and classified as Fickian diffusion (n ≤0.5), case-II transport (n = 1), anomalous transport (0.5<n<1), and super case-II transport (n>1)

Table 3: Kinetics of in-vitro release profile of STP and HI443 from solid lipid nanoparticles (SLNs).

Goto home»