Method Taken μg/mL Added μg/mL Found μg/mL Recovery % ± R.S.D. F-value t-test
Spectrophotometric BCG 3.0   2.97 99.00 ± 0.90a 1.65 2.32
    3.0 5.95 99.33 ± 0.72b 1.06 1.93
    6.0 8.95 99.66 ± 0.88b 1.58 1.14
    9.0 12.02 100.55 ± 0.83b 0.98 0.40
    12.0 15.00 100.25 ± 1.37b 3.83 0.05
           
CR 3.5   3.52 100.57 ± 0.58a 1.46 0.59
    3.5 7.06 101.14 ± 1.25b 3.19 1.17
    7.0 10.55 100.43 ± 0.66b 1.12 0.27
    10.5 13.98 99.62 ± 1.49b 4.53 0.83
    14.0 17.50 99.86 ± 0.88b 1.58 0.55
           
MO 4.0   3.96 99.50 ± 0.74a 1.12 1.57
    4.0 7.93 99.25 ± 0.68b 1.06 2.15
    8.0 11.92 99.50 ± 0.91b 0.59 1.41
    12.0 16.01 100.42 ± 0.43b 2.78 0.29
    16.0 20.10 100.88 ± 0.72b 1.06 0.50
Chromatography          
  3.0   2.99 99.67 ± 0.87a 1.54 1.80
    3.0 5.98 99.66 ± 0.89b 1.62 1.30
    6.0 8.95 99.33 ± 0.75b 0.49 0.51
    9.0 12.02 100.33 ± 0.92b 1.73 0.03
    12.0 15.03 100.33 ± 1.96b 0.13 0.03
Reported       100.30 ± 0.70  
(a) Using calibration curve method & (b) using standard addition method Theoretical F-value=6.6 and t-test=2.45 at 95% confidence limit for n1=4 and n2= 4
Table 3: Determination of SUL in dogmatil fort® tablets (200 mg/tablet) by the described spectrophotometric, and chromatographic methods compared to its determination by a reported membrane selective electrode methods [22].