QC (µg/mL) Mean measured concentrations (µg/mL) (n=5) RE (%) CV (%) Acceptance criteria
Propofol 0.005 0.0059 18.03 3.07 <20%
1 1.009910.6835100.4091 0.99 0.83 <15%
10 6.84 0.84
100 0.41 0.54
Non-conjugated metabolites 0.005 0.0052 4.87 7.00 <20%
0.5 0.51105.101351.1131 2.20 1.07 <15%
5 2.03 2.64
50 2.23 0.19
QC- Quality control; RE- Relative error; CV- Coefficient of variation
Table 4: Within-run accuracy and within-run precision data. QC means quality control, RE relative error and CV is the coefficient of variation (n =5).
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