Matrix (n=4) Amount added
(µg/mL or µg/g )
Recovery, % (CV, %)
Propofol Non-conjugated metabolites
Plasma 0.5 116.7 (1.6) 101.8 (2.5)
Liver 0.5 91.5 (1.9) 91.8 (1.7)
Lung 0.5 88.5 (7.7) 97.8 (3.5)
Kidney 0.5 94.4 (1.2) 93.3 (1.3)
Heart 0.5 108.1 (6.1) 87.9 (0.4)
Table 7: Propofol and its non-conjugated metabolites were recovered from each matrix (plasma, liver, lung, kidney and heart) supplemented at 0.5 µg/mL or 0.5 µg/g.
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