Signal Assignment Chemical Shift [ppm] T1 [S]
(R/S) in solution AB EC01 EC03
R S R S R S
HA/A’ 7.56 2,28 2,07 1,71 1,90 2,22 2,02 1,96
HB/B’,D 7.47 2,29 2,07 1,66 1,79 2,20 2,03 1,93
HC 7.39 3,13 2,45 1,95 1,99 2,52 2,2 2,24
HE,F 7.25 2,31 2,09 1,80 1,85 2,21 2,02 2,02
HG 3.83 2,21 1,99 1,69 1,83 2,15 1,94 1,86
-CH3 1.52 0,93 1,14 1,30 1,21 1,24 0,98 0,95
Table 2: Spin-lattice relaxation times (T1) for the (R)- and (S)-flurbiprofen enantiomers in solution and together with the CSP materials used. The estimated errors are approximately within ± 5%. The signal assignment in this table was performed in reference to the analyte structures presented in Figure 1.