Group Mean ± SEM age (years) Sex Mean ± SEM PMI (hr) Median Braak Score
NC 86.3 ± 1.4 N=15; 4M, 11W 2.8 ± 0.2 I
PCAD 85.8 ± 1.7a N=14; 3M, 11W 2.8 ± 0.2 Vc
MCI 91.0 ± 1.9a,b N=7; 2M, 5W 2.6 ± 0.2 IVc
LAD 80.8 ± 1.4a N=15; 7M, 8W 3.6 ± 0.4 VIc
DC 68.9 ± 4.8 N=12; 7M, 5W 3.5 ± 0.4 IIc
aP < 0.05 compared to DC
bP < 0.05 compared to LAD
cP ≤ 0.05 compared to NC
NC=Normal Control; MCI=Mild Cognitive Impairment; PCAD=Preclinical Alzheimer’s Disease; LAD=Late-stage Alzheimer’s Disease; DC=Diseased Control; PMI=Postmortem Interval.
Table 1: Subject demographic.