Analyte
Dose(U/kg）
T
max
(h)
C
max
（ng/ml)
AUC
0-t
(h*ng/ml)
Glargine
0.5
1.33
0.38
0.55
1.0
1.33
0.53
1.50
2.0
3.20
0.49
2.35
M1
0.5
2.67
1.64
5.45
1.0
2.83
1.91
10.35
2.0
4.50
2.14
18.48
Table 4:
Summary of toxicokinetics parameters in dog toxicology study after subcutaneous injection of glargine (n=6).
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