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Figure 4: Histopathological examination of hippocampal injury following exposure to glutamate in adult mice. The histopathology of the animal hippocampi was studied on day 1 after the exposure of 10-day MSG (1.0, 2.0, 4.0 g/kg/d ig). A. Control, ×50; B. MSG (1.0 g/kg per day), ×50; C. MSG (2.0 g/ kg per day), ×50; D. MSG (4.0 g/kg per day,), ×50. Arrows: a. degeneration and necrosis of neurons; b. intracellular edema. |