Gene GO category Fold change (-) Gene expression/ Function
Pou5f1 (POU domain, class 5, transcription factor 1) Nucleus; gene expression; regulation of gene expression; cell differentiation 6.04 SSC Self-renewal [21]
Zbtb16 (Plzf) (zinc finger and BTB domain containing 16) reproduction; nucleus; germ cell development; spermatogenesis; regulation of gene expression; reproductive process; cell differentiation 3.59 SSC Self-renewal [22]
Etv5 (Ets variant gene 5) nucleus ; regulation of gene expression 2.41 SSC Self-renewal [23]
Bcl6b (B cell CLL/lymphoma 6, member B) nucleus ; regulation of gene expression 7.67 SSC Self-renewal [24]
Nanos 2 reproduction; spermatogenesis ; regulation of gene expression; reproductive process ; cell differentiation 7.6 Maintaining undifferentiated state of SSCs [25]
Nanos 3 reproduction ; spermatogenesis ; regulation of gene expression ; reproductive process ; cell differentiation 6.47 Germ cell development [26]
Sohlh1(Spermatogenesis-and oogenesis-specific basic helix-loop-helix-containing protein 1 reproduction ; nucleus ; spermatogenesis ; gene expression ; regulation of gene expression ; reproductive process ; cell differentiation 2.26 Essential for spermatogonial differentiation and expressed in type A spermatogonia  [27]
Cyp26b1(Cytochrome P450 26B1) reproduction ; spermatogenesis ; reproductive process ; cell differentiation 4.29 Expressed in sertoli cells, Meiosis inhibitory factor [28]
Sox2(SRY-box containing gene 2 reproduction ; nucleus ; gene expression ; regulation of gene expression ; reproductive process ; cell differentiation 2.10 Pluripotency marker  [24]
Table 4: Genes from different GOs: fold change down-regulation (-) of genes from microarray experiment and their reported expression or function in the context of spermatogenesis.
Goto home»