| Variables |
p53 R282W mutation |
Chi square |
df |
p-value |
| |
+VE (%) |
-VE (%) |
|
|
|
| Number of Cases(100) |
58(58%) |
42(42%) |
4.5 |
1 |
0.03 |
| Gender |
| Males |
37(61.6) |
23(38.3) |
0.49 |
1 |
0.48 |
| Females |
21(52.5) |
19(47.5) |
| Age |
| <20 yrs |
8(72.7) |
3(27.2) |
1.66 |
3 |
0.64 |
| 20-30 yrs |
12(57.1) |
9(42.8) |
|
|
|
| 30-40 yrs |
16(61.5) |
10(38.4) |
|
|
|
| >40 yrs |
22(52.3) |
20(47.6) |
|
|
|
| Phase |
| Chronic |
31(35.2) |
37(64.7) |
13.5 |
2 |
0.001 |
| Accelerated |
14(88.2) |
3(11.7) |
|
|
|
| Blast Crisis |
13(60.0) |
2(40.0) |
|
|
|
| TLC |
| <20,000 |
17(42.5) |
23(57.5) |
6.41 |
1 |
0.011 |
| >20,000 |
42(70.0) |
18(30.0) |
|
|
|
| Platelet Count |
| Normal count |
19(39.5) |
29(60.4) |
12.85 |
2 |
0.0016 |
| Thrombocytopenia |
27(75.0) |
9(25.0) |
| Thrombocytosis |
12(75.0) |
4(25.0) |
| Spleen size |
| Spleenomegaly present |
43(65.0) |
23(34.8) |
3.26 |
1 |
0.07 |
| Spleenomegaly absent |
15(44.1) |
19(55.8) |
| Haematological Response (HR) |
| Major HR |
7(33.3) |
14(66.6) |
8.1 |
2 |
0.017 |
| Minor HR |
10(52.6) |
9(47.3) |
| Minimal HR |
41(68.3) |
19(31.6) |
|
