DOX=Doxorubicin, S1P=Sphingosine-1-Phosphate, LDH=Lactate
Dehydrogenase
. LDH assay was performed as described in
the method section. Results are shown as mean ± SEM. N ≥ 32, *=P<0.05,
***=P<0.001.| DOX=Doxorubicin, S1P=Sphingosine-1-Phosphate, LDH=Lactate
Dehydrogenase |
| Figure 1: S1P protection against DOX after 72 h incubation. The ability of
S1P to protect the cells was a combination of two factors, DOX concentration
and S1P concentration. Data normalized according to the following equation
for calculating cytotoxicity (%) supplied by the LDH kit manufacturer. . LDH assay was performed as described in
the method section. Results are shown as mean ± SEM. N ≥ 32, *=P<0.05,
***=P<0.001. |
