and shown as mean ± SEM. N≥42, **=P<0.01. |
| Figure 2A: The effect of cyclophosphamide on GCs after 72 h incubation.
CPA induced significant cell death compared to control at all the tested
concentrations. CPA 1 mg/ml and 2 mg/ml were significantly cytotoxic relative
to control, while CPA 0.5 mg/ml was significantly less cytotoxic than control.
At all CPA concentrations, S1P had no effect. LDH assay was performed as
described in the method section. Results are normalization to Triton X-100, and shown as mean ± SEM. N≥42, **=P<0.01. |
