| Figure 2B: S1P may protect GCs against CPA induced cytotoxicityrepresentative
graph. S1P protected the GCs by decreasing cell death. CPA
0.5 mg/ml had, in this experiment, a small, statistically significant effect on
the cells. On the other hand, CPA 2 mg/ml caused significant cell death and
S1P abolished this effect completely. Right: The crude data shown as ΔOD,
Left: The results normalized to Triton X-100. LDH assay was performed
as described in the method section. Results shown as mean ± SEM. N=6,
*=P<0.05, ***=P<0.001. |
CPA=Cyclophosphamide, S1P=Sphingosine-1-Phosphate, OD=Optical
Density, LDH=Lactic Dehydrogenase