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| Figure 4b: MSC impair NK cell lytic functions. CD107a degranulation by NK cells against IFN-primed MSC. NK cells were cultured with MSC (ratio NK/MSC, 5:1) for 4h in presence of anti- CD107a antibody and Monensin (2 μM). K562 cell line was used as positive control. One representative out of 5 independent experiments is presented. Data are shown as box plots. Each box represents the 25th to 75th percentiles. Lines outside the boxes represent the minimum and maximum values. Lines inside the boxes represent the mean. |
