Table 1 | The 3 miRNA model provides a sensitive..

miRNA species	Specificity	Sensitivity	Accuracy	area under the curve
miR-29c	80%	92%	86.9%	0.892
miR-30-5p	90%	62%	73.9%	0.762
miR-424	100%	92%	94.7%	0.927
miR-29c miR-30-5p	100%	77%	87.0%	0.931
miR-29c + miR-424	100%	83%	90.0%	0.969
miR-30-5p + miR-424	100%	83%	90.0%	0.969
miR-29c + miR-30-5p + miR-424	100%	92%	95.0%	0.979

The concentrations of individual miRNA assessed by quantitative RT-PCR (data not shown) were used in the ROC analysis. The table presents results from ROC analysis using individual miRNA species or using a combination of 2 or all 3 miRNA species (the 3 miRNA model).

Table 1: The 3 miRNA model provides a sensitive and specific criterion for distinguishing true PD from non-PD among patients with suspected PD.

Goto home»