Figure 7: LPS maintains potency after incubation in osmotic minipump. Cultured BV-2 microglia cells responded to fresh LPS as well as LPS that had been incubated in an Alzet osmotic minipump for 4, 6 or 8 weeks (at 37°C in 0.9% saline bath) with the release of similarly increased levels of NO, as compared to un-stimulated cells (§ p<0.003). |