MCI versus normal aging |
Unit |
Odds Ratio (95%CI) |
Significance |
Non-PVC model |
gender |
1 |
1.855 (0.995 - 3.462) |
0.0521 |
education |
2.9586 |
0.881 (0.655 - 1.185) |
0.4027 |
age |
6.5536 |
0.597 (0.439 - 0.812) |
0.001 |
entorhinal |
337.3 |
0.681 (0.478 - 0.970) |
0.0335 |
banks STS |
341.8 |
0.773 (0.558 - 1.071) |
0.1214 |
caudal middle frontal |
876.3 |
0.742 (0.538 - 1.023) |
0.0687 |
inferior temporal |
1279 |
0.744 (0.520 - 1.064) |
0.105 |
superior temporal |
1166.3 |
1.418 (0.948 - 2.122) |
0.0894 |
hippocampus |
532.6 |
0.345 (0.222 - 0.537) |
<0.0001 |
Cortical thickness + subcortical volume residuals |
gender |
1 |
1.131 (0.645 - 1.985) |
0.6677 |
education |
2.9586 |
0.907 (0.703 - 1.171) |
0.4536 |
age |
6.5536 |
0.815 (0.625 - 1.064) |
0.1331 |
paracentral gyrus |
371.1 |
1.261 (0.949 - 1.674) |
0.1094 |
temporal pole |
225.5 |
1.478 (1.134 - 1.927) |
0.0039 |
amygdala |
21.0682 |
0.667 (0.499 - 0.890) |
0.0059 |
Gray matter mask |
gender |
1 |
1.507 (0.869 - 2.612) |
0.1444 |
education |
2.9574 |
0.857 (0.658 - 1.117) |
0.2539 |
age |
6.4782 |
0.798 (0.611 - 1.041) |
0.0965 |
entorhinal |
1349.3 |
0.549 (0.361 - 0.835) |
0.0051 |
fusiform |
1235.9 |
2.439 (1.342 - 4.434) |
0.0035 |
inferior temporal |
1301 |
0.576 (0.341 - 0.975) |
0.04 |
isthmus of the cingulate |
2007.9 |
0.588 (0.386 - 0.895) |
0.0133 |
The top model shows the non-pvc model (c = 0.810), followed by the cortical thickness + subcortical volume residuals (c = 0.678), and the GMM on the bottom (c = 0.688). |