Authors Year Reference Methods Number of subjects Al detection AD control Masters et al. 1985 [130] EDX 6 - + Candy et al. 1986 [138] EDX, SIMS 7 - + Jacobs et al. 1989 [113] EDX 7 4 - Larsson et al. 1990 [139] Proton microprobe 2 - - Moretz et al. 1990 [132] EDX 3 - - Senitz and Blüthner 1990 [140] Morin staining 3 - + Chafi et al. 1991 [133] WDX, SIMS 7 - - Landsberg et al. 1992 [141] Proton (nuclear) microscopy 5 2 - Landsberg et al. 1993 [142] Proton (nuclear) microscopy 6 2 ± Kasa et al. 1995 [135] solachrone azurine 10 5 ± Yumoto et al. 2009 [143] TEM-EDX 5 - + EDX: energy-dispersive X-ray spectroscopy; WDX: wavelength-dispersive X-ray microanalysis; SIMS: secondary ion mass spectrometry; TEM-EDX: energydispersive X-ray spectroscopy combined with transmission electron microscopy.

Table 6: Detection of Al in senile plaques of AD brain tissues.

Goto home»