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Figure 5: Inflammatory mediators in postmortem brains-1. Frontal lobe aqueous homogenates from subjects with Braak Stage (B) 0-1 (controls), B3-4 (moderate AD), or B6 (late AD) pathology (N=8/group) were used to measure (A) Interleukin-1β, (B) Interleukin-6, (C) Interleukin-8, (D) Interleukin-10, (E) Interleukin-16, (F) Interleukin-18, (G) Tumor necrosis factor-α (TNF-α), and (H) TRAIL by multiplex bead-based ELISA. Immunoreactivity is expressed in fluorescence light units (FLU) normalized to protein content. Data were analyzed by one-way repeated measures ANOVA with post hoc Fisher significance tests.
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