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| Figure 6: Inflammatory mediators in postmortem brains-2. Frontal lobe aqueous homogenates from subjects with Braak Stage (B) 0-1 (controls), B3-4 (moderate AD), or B6 (late AD) pathology (N=8/group) were used to measure (A) LIF-1, (B) scatter factor (SCF), (C) (MCP), (D) SDF, (E) GMCSF, (F) MIP-1, (G) Interferon-γ, and (H) (IP-10) by multiplex bead-based ELISA. Immunoreactivity is expressed in fluorescence light units (FLU) normalized to protein content. Data were analyzed by one-way repeated measures ANOVA with post hoc Fisher significance tests. |
