Animal Age [post-natal days] Number of animal per group tNAA [mM] Glx [mM] tCr [mM] tCho [mM] Tau [mM] Ins [mM]
4-6 10 2.04  ± 0.03 5.02 ± 0.02 4.40  ± 0.08 1.62 ± 0.01 14.97 ± 0.09 5.15 ± 0.06
10-12 15 3.57 ± 0.32*** 7.62 ± 0.46 *** 5.51 ± 0.10 *** 1.39 ± 0.01*** 12.92 ± 0.68** 2.69 ± 0.13***
14-18 18 5.97 ± 0.66*** 10.45 ± 0.74*** 6.55 ± 0.61*** 1.22 ± 0.13 9.03 ± 1.39*** 2.37 ± 0.25
19-21 14 6.95 ± 0.62** 12.33 ± 0.52** 7.80 ± 0.35*** 1.51 ± 0.13 7.83 ± 1.197 2.49 ± 0.24
24-57 24 6.89 ± 0.38 13.09 ± 0.68 7.45 ± 0.18 1.70 ± 0.03 5.72 ± 0.51 4.28 ± 0.37***
Significant differences between subsequent time-points in groups of mice are marked with asterisks (*: p<0.05; **: p<0.01; ***: p<0.001)
Table 2: Concentrations of cerebral metabolites measured with proton MR spectroscopy in mice. Data given here represent mean values (± SEM) averaged over all mice that were measured within certain age ranges. Calculation of SEM values for age ranges was performed taking into account the uncertainties of each individual measurement.
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