| Score |
Staging |
| Frontal and temporal lobes |
|
| 0 |
Normal appearance of brain, vessels, white matter, and cortex |
| I |
Mild modification of vessel walls, perivascular spaces, or white matter |
| II |
Moderate to severe but isolated modification of the vessel walls (arteriolosclerosis or amyloid angiopathy), usually associated with hemosiderin deposits in the perivascular spaces |
| III |
Moderate to severe perivascular space dilatations either in the deep or the juxtacortical white matter |
| IV |
Moderate to severe myelin loss |
| V |
Presence of cortical microinfarcts |
| VI |
Presence of large infarcts |
| Hippocampus |
|
| 0 |
Normal appearance |
| I |
Mild modification of vessel walls or perivascular spaces |
| II |
Moderate to severe perivascular space dilatations |
| III |
Presence of microinfarcts (usually in Ammon horn or the subiculum) |
| IV |
Presence of large infarcts |
| Basal ganglia |
|
| 0 |
Normal appearance |
| I |
Mild modification of vessel walls or perivascular spaces |
| II |
Moderate to severe perivascular space dilatations |
| III |
Presence of microinfarcts |
| IV |
Presence of large infarcts |
| Total vascular score |
Frontal + temporal lobe + hippocampus + basal ganglia (/20) |
