Reference |
Disease |
Case Definition for TBI |
Methodology |
OR |
Relevant Findings |
Fratiglioni et al 199327 |
AD |
LOC |
Interview an “informant” of the patient |
.4 |
|
Mayeux et al 199530 |
AD |
LOC |
Interview |
1.5 |
OR: 10.5 for e4 carriers |
Guo et al 2000278 |
AD |
LOC or medical attention |
Structured questionnaire |
4.6 |
OR: 9.9 for TBI with LOC |
Plassman et al 200032 |
AD |
Medical record of LOC, post-traumatic amnesia or skull fracture occurring during military service |
Military health records |
2.16 |
|
Chen et al 200719 |
ALS |
Injury requiring medical attention |
Interview |
1.4 |
OR:3.1 for head injury in 10 years leading up to onset of ALS |
Schmidt et al 2010231 |
ALS |
LOC or medical care |
Telephone interview |
1.26 |
OR: 1.88 for TBI occurring at older age (>29) |
Turner et al 2010233 |
ALS |
N/A |
Reviewed data from Oxford Record Linkage Data |
1.5 |
|
Stern et al 1991146 |
PD |
Head trauma severe enough to cause vertigo, dizziness, blurred vision, seizure or convulsion, transient memory loss, personality change or paralysis |
Structured interview |
2.9 |
|
Martyn and Osmond 1995155 |
PD |
LOC or hospital admission |
Standardized questionnaire |
.6 |
|
Kuopio et al 1999154 |
PD |
N/A |
Interview |
.89 |
OR:1.99 for multiple TBI
OR:1.37 for TBI with LOC |
Taylor et al 1999147 |
PD |
Head trauma severe enough to cause LOC, blurred/double vision, dizziness, seizures, or memory loss |
Structured interview |
5.09 |
|
Tsai et al 2002148 |
PD |
Head trauma severe enough to cause vertigo or dizziness, LOC, post-traumatic amnesia, personality changes, seizures or paralysis |
Structured Questionnaire |
9.27 |
OR: 4.5 for young onset PD (< 40 years of age) compared to normal PD patients |
Zorzon et al 2002162 |
PD |
LOC |
Structured interview |
1.6 |
|
Baldereschi et al 2003 150 |
PD |
LOC |
Standardized questionnaire interview |
.85 |
|
Bower et al 2003140 |
PD |
LOC, posttraumatic amnesia, neurologic signs of Brain Injury, or Skull fracture with documented medical record |
Medical history screened by nurse and confirmed by neurologist |
4.3 |
OR:11 for TBI with LOC
TBI with Hospitalization:
8 |
Goldman et al 2006143 |
PD |
Amnesia or LOC following head injury |
Phone interview |
3.6 |
OR:4.3 for multiple TBI
OR:4.1 for TBI resulting in hospitalization |
Dick et al 2007141 |
PD |
“Ever being knocked unconscious” |
Standardized questionnaire interview |
1.35 |
OR: 2.53 for multiple TBIs with LOC |
Fang et al 2012279 |
PD |
Hospitalization |
Medical records |
1.94 |
|
Lee et al 2012280 |
PD |
LOC > 5 minutes in duration |
Interview |
2 |
|
Goldman et al 2012167 |
PD |
Affirmative response to “Have you ever had a head injury where you lost consciousness or were diagnosed with a concussion by a doctor?” |
Computer assisted phone interview |
1.3 |
OR: 3.5 for Long Rep1 allele carries with TBI history |
Harris et al 2013281 |
PD |
Injury requiring physician attention |
Standardized questionnaire interview |
2.08 |
OR: 2.64 for TBI with LOC |