Gene Name (common name) Expression Pattern* Verified by immunoblot
ALDOA (Fructose-bisphosphatealdolase A) Neurons only  
ARF1 (ADP-ribosylation factor 1) Neurons only  
CLTC (Clathrin heavy chain 1) Neurons only  
DNM1 (Isoform 3 of dynamin 1) Neurons only  
ENO1 (Alpha enolase) Neurons only Yes
ENO2 (Gamma enolase) Neurons only Yes
PGAM1 (Phosphoglycerate kinase 1) Neurons only Yes
NSF  (Vesicle fusing ATPase) Neurons only  
STXBP1 (Isoform 1 syntaxin-binding protein 1) Neurons only  
YWHAB (Isoform long of 14-3-3 protein beta/alpha) Neurons only  
YWHAG (14-3-3 protein gamma) Neurons only  
YWHAH (14-3-3 protein eta) Neurons only Yes
YWHAZ (14-3-3 protein zeta/delta) Neurons only  
ACO2 (Aconitatehydratase, mitochondrial) Neurons and White Matter  
ACTC1 (Actin, alpha cardiac muscle 1) Neurons and White Matter  
CKB (Creatine kinase B-type) Neurons and White Matter  
DPYSL2 (Dihydropyrimidinase-related protein 2) Neurons and White Matter  
EEF1A1(Elongation factor 1-alpha 1) Neurons and White Matter  
GAPDH (Glyceraldehyde-3-phosphatase dehydrogenase) Neurons and White Matter Yes
GDI1 (Rab GDP dissociation inhibitor alpha) Neurons and White Matter  
HSPA8 (Heat shock cognate 71 protein) Neurons and White Matter  
HSP90AA1 (Heat shock protein 90-alpha) Neurons and White Matter  
HSP90AB1 (Heat shock protein 90-beta) Neurons and White Matter  
PGK1(Phosphogycerate kinase 1) Neurons and White Matter  
YWHAE (14-3-3 protein epsilon) Neurons and White Matter  
YWHAQ (Isoform 1 of 14-3-3 protein theta) Neurons and White Matter  
APOE (Apolipoprotien E) Astrocytes  
CKB (Creatine Kinase B-type) Astrocytes  
CLU (Clusterin) Astrocytes Yes
EEF1A1 (Elongation factor 1-alpha 1) Astrocytes  
*Expression pattern assessed by the Allen Brain Atlas (http://mouse.brain-map.org)
Table 1: Characteristics of proteins that lose solubility in older APPswe/PS1dE9 mice
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