Parkinson’s disease patients with apathy
(n = 22)
Parkinson’s disease patients without apathy
(n = 39)
Healthy Controls
(n=19)
Statistic (ANOVA or t-test)
  Mean (SD) F; p
Verbal fluency, (FAS; adjusted for age, sex and education) 35.27
(10.46)
41.62
(15.13)
53.31
(12.42)
F = 7.41;
p=0.001
###‡
Attention
(Serial 7’s)
3.36
(1.79)
4.34
(0.76)
5.16
(0.69)
F=19.21;
p < .001
### ‡‡‡
mWCST2 Total 34.05
(6.10)
34.15
(10.52)
38.63
(8.41)
3.15
p = 0.21
mWCST2: perseverative errors 4.86
(5.65)
4.15
(6.02)
1.53
(2.76)
3.44
p = 0.18
mWCST2: non-perseverative errors 19.19
(8.57)
18.15
(10.94)
16.42
(10.70)
.64
p = 0.73
5 minute recall 2.18
(1.01)
2.51
(0.85)
2.74
(0.99)
4.43
p = 0.11
n-back
(correct responses)
13.27
(3.21)
16.09
(3.32)
18.89
(3.31)
F = 13.38
p< 0.001
###  ‡‡
TMT3-B-TMT-A, (seconds) 132.36
(85.86)
83.0
(57.27)
62.16
(31.50)
21.16
p< .001
† ###  ‡‡‡
Post-hoc Scheffe or Mann Whitney U for two-group comparison:
PD+A vs. HC: # at p<0.05; ## at p<0.01; ### at p<0.001;
PD-A vs. HC: ‡ at p<0.05; ‡‡ at p<0.01; ‡‡‡ at p<0.001;
PD+A vs PD-A: † at p<0.05;†† at p<0.01;††† at p<0.001
1Mini-mental State Exam; 2Modified Wisconsin Card Sorting Test; 3Trail making test
Table 3: Comparison of cognitive measures in three groups: Parkinson’s disease participants with and without apathy; healthy controls (HC).
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