| Sleep parameters |
Baseline |
After treatment with donepezil |
| Total sleep time (min) |
428.0 ± 113.6 |
435.0 ± 57.3 |
| Sleep period time (min) |
482.0 ± 83.6 |
492.4 ± 44.9 |
| Sleep latency (min) |
65.6 ± 82.8 |
33.6 ± 40.1 |
| Sleep efficiency* |
76.2 ± 16.3 |
82.8 ± 10.6 |
| Time of wake after sleep onset %SPT† |
15.7 ± 10.0 |
11.7 ± 7.7 |
| Stage 1, %TST |
22.4 ± 13.6 |
17.5 ± 6.0 |
| Stage 2, %TST |
63.6 ± 12.4 |
63.8 ± 7.7 |
| Stage 3, %TST |
2.4 ± 3.0 |
1.3 ± 1.1 |
| Stage 4, %TST |
0.3 ± 0.7 |
0.1 ± 0.3 |
| Stage REM %TST** |
11.3 ± 4.1 |
17.1 ± 4.4 |
| REM sleep latency (min) |
103.7 ± 55.9 |
70.4 ± 28.5 |
Mean ± SD †p<0.1; *p<0.05; **p<0.01; TST: total sleep time; SPT: sleep period
time; REM: rapid eye movement |
