Gene Chromosome AD category Age of onset
Presenilin I 14 Early onset familial AD 25-60 years
APP 21 Early onset familial AD 40-64 years
Presenilin II 1 Early onset familial AD 45-84 years
APOE e4 19 Early to late onset familial and sporadic AD >50 years
Table1: Genes involved in Alzheimer’s disease [6-9]
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