Ischemic regional function |
|
Thickness (d) (cm) |
Thickness (s) (cm) |
Thickening (%) |
WMS |
|
Baseline |
0.658±0.073 |
1.094±0.139 |
66.2±6.3 |
1.00±0.00 |
|
DSE (3 months) |
|
|
|
|
|
Rest |
0.786±0.096 |
1.324±0.059 |
70.9±25.1 |
1.00±0.00 |
|
Low Dosage |
1.040±0.200 |
1.674±0.221 |
63.4±22.1 |
2.00±0.63 |
|
High Dosage |
0.987±0.189 |
1.484±0.437 |
49.7±30.7 |
2.33±0.82 |
|
Recovery |
0.861±0.109 |
1.292±0.207 |
49.9±13.1 |
1.83±0.41 |
|
|
|
|
|
|
|
Left ventricular global function |
|
LVDd (cm) |
LVDs (cm) |
FS (%) |
CO (l/min) |
HR (bpm) |
Baseline |
4.27±0.45 |
2.84±0.30 |
33.3±4.6 |
2.97±1.15 |
115±23 |
DSE (3 months) |
|
|
|
|
|
Rest |
5.29±0.33 |
3.26±0.24 |
38.3±5.2 |
4.92±1.19 |
85±12 |
Low Dosage |
4.49±0.82 |
2.13±0.49 |
52.4±6.9* |
7.38±0.64 |
122±20 |
High Dosage |
4.42±0.46 |
2.23±0.62 |
49.8±11.0* |
9.22±0.66 |
136±61 |
Recovery |
4.81±0.47 |
3.15±0.30 |
34.3±5.6 |
5.24±1.42 |
98±10 |
CO=cardiac output; DSE=dobutamine stress echocardiography at 3 months; FS=fractional shortening; LVDd=left ventricular dimension (at end-diastole); LVDs=left ventricular
dimension (at end-systole); TTE=transthoracic echocardiography; WMS=wall motion score. *P<0.05 compared to rest. |