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| Figure 2: MCF-7 tumor xenografts evolution versus time. Five groups of mice were studied: the first group was not treated (Δ), the second one was weekly injected with drug-free MFLs (☐), the last three other groups were weekly treated (4.3mg RU/week/kg), either in glucose 5% solution (▽) or incorporated within MFLs with (●) or without (○) a 0.44-T external magnet (155 T/m magnetic field gradient) placed onto the tumor for 4 hours after injection. Tumor growth was reported by the ratio of average median volume (V) measured for each animal group on week n (n=1-7) to that measured on week 0 (V0); symbols * and **mean p<0.01 and p<0.001, respectively. |
