Figure 3: Pharmacokinetics basics (panel A) as compared with phage therapy basics (panel B). Phage therapy as typically practiced often differs in two basic ways from the ‘life cycle’ of most drugs (panel A). First, absorption, that is, uptake into the blood, is not an issue for the sake of positive pharmacodynamic effects unless systemic treatment is sought. Second, most drugs, unlike phages, do not self amplify in situ following contact with target tissues.
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