Pharmacokinetic Parameter

Treatment (Mean ± SD)

Test Product

Reference Product

Cmax (ng/ml)

2993±845.18

3319±675.16

AUC0→t (ng.h/ml)

15423.8±5431.72

17163.9±4192.24

AUC0→∞(ng.h/ml)

16008.5±5582.25

17874.2±4318.83

tmax (h)

2.10±0.82

2.13±0.58

t½e (h)

5.25±1.29

5.24±0.99

AUC0→t /AUC0→∞%

96.23±1.24

95.97±1.97

Ke (1/h)

0.1379±0.03

0.1369±0.03

Table 6: Pharmacokinetics Parameters of Ciprofloxacin for fasting study (Ciprofloxacin XR Tablet the Test Product versus Cipro XR Tablet the Reference Product).