Exposure time of PC

Groups

Means± SEM

 

4 weeks

 

C

B

 

2.0± 0.152

2.12± 0.555a

 

8 weeks

 

C

B

 

2.23± 0.787

3.15± 0.443b

 

12 weeks

 

C

B

 

2,55± 0.199

4.01± 0.327b
aSignificance of the results, p≤0.05 comparison of control
bSignificance of the results, p≤0.001 comparison of control

Data represent the means ± SEM; n=10, and were analyzed with student t-test. Abbreviations: C-control (untreated) group, B – (study group) rats were given paracetamol (acetaminophen) solution to drink by intra-oesophageal instillation in a dose of 2.4 g/kg of body weight/24 hrs (i.e. 16 μmol/kg of body weight/24 hrs), after drinking it, they had unlimited access to distilled water

Table 2: Malondialdehyde (MDA) concentration in rat liver.
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